- "This is beyond me. I think we'd better call Washington"
- —Daniel Ripley[src]
Doctor Daniel "Dan" Ripley is a doctor who resided in a suburb in the United States of America, running his own practice as the neighborhood doctor.
Daniel worked in a suburb in the United States of America on Earth during the 1950s, living with his wife and daughter, Alicia. When Matthew Webber and Lou Ann brought an extraterrestrial life form with a Xenomorph Facehugger attached to his face into Ripley's office, the Chestburster inside him emerged from his chest and escaped into the forest around the suburb.
While the Xenomorph grew into a Queen and began creating a Hive, Ripley and his wife, and Alicia, attempted to flee the suburb in their car, however, they were attacked en route by the Queen. The Xenomorph was killed when the car caught fire and exploded as the family fled to the forest. In the woods, they discovered the Hive, which consisted of Eggs and bikers impregnated by Facehuggers. The family were soon surrounded by an outlaw biker gang and, together, they managed to destroy the Hive by incinerating it. Afterwards, the Ripleys made it to Daniel's mother-in-law's house, completely exhausted by the events that had transpired.
- Daniel's surname "Ripley" indicates that he and his family are ancestors to Ellen Ripley, who too would face Xenomorphs in her lifetime.